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to irritate
01
to annoy someone, often over small matters
Transitive: to irritate sb
Example
The way he constantly interrupts conversations can really irritate people.
The dog 's persistent barking began to irritate the neighbors.
02
to cause discomfort or inflammation in a body part
Transitive: to irritate a body part
Example
The soap irritated her skin, causing a rash.
His eyes were irritated because of the dust in the air.
03
to trigger an active response from an organism, cell, or organ by stimulating it
Transitive: to irritate an organism or cell
Example
The injection irritated the immune system, causing it to release antibodies.
The bacteria irritated the cells, triggering an inflammatory response.