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to antagonize
01
to provoke and anger someone so much that they start to hate and oppose one
Transitive: to antagonize sb
Examples
His constant criticism of her work antagonized her to the point of seeking employment elsewhere.
02
(of a substance) to oppose or counteract the action of another substance
Transitive: to antagonize a substance or its effect
Examples
The medication antagonized the effects of the painkiller, making it less effective.
