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adverse
01
against someone or something's advantage
Example
The adverse effects of smoking on health are well-documented.
Experiencing adverse reactions to medication can be dangerous and require medical attention.
The adverse economic conditions led to layoffs and financial hardship for many families.
02
moving or directed in an opposing direction
Example
The river 's adverse currents made it difficult for the kayakers to make progress upstream.
The plane took off despite the adverse flow of wind, showcasing the pilot's expertise.