Vicissitude

/vˈɪsɪsˌɪtjuːd/

/ˌvɪˈsɪsɪtud/

Vicissitude

mutability in life or nature (especially successive alternation from one condition to another)

a variation in circumstances or fortune at different times in your life or in the development of something

Examples

1. It is vicissitude.

2. And experienced a number of vicissitudes inherited with that as well.

3. The hard times and vicissitudes of life will ultimately visit everyone.

4. The hard times and vicissitudes of life will ultimately visit everyone.