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Vicissitude
01
mutability in life or nature (especially successive alternation from one condition to another)
02
the unpredictable changes or fluctuations in circumstances, often involving alternating periods of success and adversity
Example
Amidst the vicissitudes of history, civilizations rise and fall, leaving behind legacies that endure through the ages.
Throughout his career, he experienced numerous vicissitudes, including both triumphs and setbacks.
We must navigate the vicissitudes of fortune with resilience and adaptability, embracing both the highs and lows as part of our journey.
Example

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