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Examples
1. Once again, this nephritic factor stabilizes the C3 convertase and allows it to keep on converting C3 to C3a and C3b.
2. These, along with inflammation, are several of the characteristic features making PSGN a nephritic syndrome.
3. All three typically lead to nephrotic symptoms, but occasionally nephritic symptoms as well.
4. Alright, as a quick recap, IgA nephropathy is the most common cause of nephropathy worldwide, and it’s a type of nephritic syndrome in which abnormal IgA1 immunoglobulin is targeted by anti-gycan auto-antibodies, forming immune complexes that are then deposited in the glomerular mesangium, which then start up a type III hypersensitivity reaction which causes glomerular injury and hematuria.
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