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Nadir
01
the moment in which a situation or life is at its lowest or worst
02
the point below the observer that is directly opposite the zenith on the imaginary sphere against which celestial bodies appear to be projected
Example
His health reached its nadir after months of neglect and stress.
The company’s profits hit their nadir during the financial crisis.
The team’s performance hit a nadir last season, with the fewest wins in years.
She realized she was at her emotional nadir after the breakup.
After losing his job and his home, he felt he had reached the nadir of his life.