Definition & Meaning of "screw over"in English

What is the origin of the term "screw over" and how is it used?

"screw over" is a slang phrasal verb that appeared in English in the mid-20th century, using the verb "screw" metaphorically to mean harming, cheating, or taking advantage of someone. It describes actions that unfairly ruin a person's chances, situation, or interests. The term is widely used in informal speech, media, workplace discussions, and casual storytelling to convey betrayal or exploitation. It is coarse and derogatory, context-dependent—acceptable in informal or emphatic situations, but offensive and inappropriate in polite or formal contexts.