Definition & Meaning of "peptic ulcer disease"

What is "peptic ulcer disease"?

Peptic ulcer disease is a condition characterized by painful wounds in the lining of the stomach or the upper part of the small intestine, known as the duodenum. These wounds can be caused by factors such as infection with Helicobacter pylori bacteria, long-term use of certain medications like pain-relieving drugs, excessive alcohol consumption, and smoking. Symptoms of peptic ulcer disease may include abdominal pain or discomfort, bloating, feeling full quickly after eating, heartburn, nausea, vomiting, and unintentional weight loss. Treatment for peptic ulcer disease typically involves medications to reduce stomach acid production, antibiotics to treat H. pylori infection if present, and lifestyle changes such as avoiding irritants like pain-relieving drugs and alcohol. In severe cases, surgery may be necessary to repair the wound or remove the affected part of the stomach or small intestine.