Renin

/ɹɪnˈɪn/

/ˈɹinən/

[noun]

Renin

[NOUN]

an enzyme involved in regulating blood pressure and fluid balance by initiating the production of angiotensin II

What is "renin"?

Renin is an enzyme produced by specialized cells in the kidneys called juxtaglomerular cells. It plays a crucial role in regulating blood pressure and fluid balance by initiating a cascade of reactions that lead to the production of angiotensin II, a potent vasoconstrictor. Renin acts as a key player in the renin-angiotensin-aldosterone system, which helps regulate blood volume, electrolyte balance, and systemic vascular resistance.

Examples

1. Renin initiates a two-step process that produces the hormone angiotensin II.

2. They also release important hormones into your body: erythropoietin, renin, and calcitriol.

3. But, as I mentioned earlier, this renin angiotensin aldosterone system is stimulated by low salt intake.

4. Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.