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The innermost planets of our solar system, Mercury and Venus, orbit closest to the Sun.
In anatomy, the innermost layer of the skin, the dermis, provides structural support and nourishment to the outer layers.
The pearl lay nestled in the innermost chamber of the oyster shell.
The innermost part of the cell, the nucleus, contains the genetic material essential for cellular function.
The innermost layer of the Earth, known as the inner core, is believed to consist mainly of iron and nickel.