Aldosterone

/ɔːldˈɒstəɹˌəʊn/

/ɔːldˈɑːstɚɹˌoʊn/

[noun]

Aldosterone

[NOUN]

a hormone produced by the adrenal glands that regulates electrolyte balance and fluid levels in the body

What is "aldosterone"?

Aldosterone is a hormone produced by the adrenal glands as part of the endocrine system. It belongs to a group of hormones called mineralocorticoids and is primarily involved in regulating electrolyte balance, particularly the reabsorption of sodium and excretion of potassium in the kidneys. Aldosterone acts on the distal tubules of the nephrons, promoting sodium retention and potassium excretion, which helps maintain blood pressure, blood volume, and overall fluid balance. Its secretion is regulated by the renin-angiotensin-aldosterone system and influenced by factors such as blood volume, sodium levels, and the presence of certain hormones. Overall, aldosterone plays a crucial role in maintaining electrolyte homeostasis and blood pressure regulation in the body.

Examples

1. Aldosterone promotes sodium and water retention in the kidneys.

2. Aldosterone increases the number of sodium channels on the lumen side of the principal cell and and sodium-potassium pumps on the basolateral side of the principal cells.

3. With these medications around, aldosterone can’t exert its effects.

4. Aldosterone is a key hormone that is secreted as part of the renin-angiotensin-aldosterone system.