Basophil

/bˈasəfˌɪl/

/bˈæsəfˌɪl/

[noun]

Basophil

[NOUN]

a type of white blood cell involved in allergic reactions and immune responses in the human body

synonyms : basophile

What is a "basophil"?

A basophil is a type of white blood cell found in the human body. Basophils are part of the immune system and play a role in allergic reactions and inflammatory responses. Basophils contain granules filled with substances such as histamine, which are released when the cell is activated. When an allergic reaction occurs, basophils are involved in the immune response by releasing histamine, which triggers the dilation of blood vessels and increases their permeability. This response contributes to the characteristic symptoms of allergies, such as itching, redness, and swelling. Basophils also participate in immune defense against parasites. While they make up a small percentage of the total white blood cell count, basophils play an essential role in the body's immune response and maintaining overall health.

Examples

1. IgE molecules bind to their receptors on the surface of mast cells and basophils.

2. IgE molecules then bind to their receptors on the surface of mast cells and basophils.

3. It is caused by a massive release of inflammatory mediators from mast cells and basophils into the circulation.

4. They occur via direct stimulation of mast cells or basophils, in the absence of immunoglobulins, and have different triggers.