What is "limb-girdle muscular dystrophy"?

Limb-girdle muscular dystrophy (LGMD) is a genetic disorder that primarily affects the muscles around the hips and shoulders. It is characterized by progressive weakness and wasting of these muscles, leading to difficulties with walking, climbing stairs, and raising the arms. LGMD can vary widely in how it starts and how intense it is, with symptoms typically appearing in childhood, adolescence, or adulthood. It is caused by changes in genes that are involved in muscle function. Treatment for LGMD focuses on managing symptoms and improving quality of life. This may include physical therapy to strengthen muscles and maintain flexibility, assistive devices such as braces or supports, and medications to address specific symptoms such as pain or fatigue. While there is currently no cure for LGMD, ongoing research may lead to new treatments in the future.