Pepperoni roll is a type of bread roll that is popular in the United States, particularly in West Virginia, where it is considered a regional specialty. It is made by wrapping a mixture of pepperoni and cheese in a soft bread dough, which is then baked until the dough is golden brown and the filling is hot and melted. The rolls are often served as a handheld snack or meal and are a popular food item at bakeries, cafes, and convenience stores in the region. Pepperoni rolls may also include other ingredients such as sausage, ham, or vegetables, depending on the recipe.

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