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Isolation

British pronunciation/ˌa‍ɪsəlˈe‍ɪʃən/
American pronunciation/ˌaɪsəˈɫeɪʃən/
Isolation
[NOUN]
1

a state of separation between persons or groups

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2

the act of to physically or socially separating someone or something from others

synonyms : closing off
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3

a feeling of being disliked and alone

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4

a country's withdrawal from international politics

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5

(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it

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Examples
1Does coronavirus need isolation?
2Involves isolation.
3- I miss isolation.
4Isolation is terrible for human beings.
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