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The alpha male led the pack of hyenas, ensuring they maintained their dominance over other predators.
The CEO was responsible for the company's alpha and omega, making critical decisions from inception to final execution.
The opening and closing paragraphs of her essay were the alpha and omega of her argument, encapsulating the main points.
The book's prologue and epilogue served as the alpha and omega, framing the narrative and giving it a complete structure.
Alpha thalassemia involves reduced or absent alpha globin chains.