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deleterious

British pronunciation/dɪlɪtˈi‍əɹɪəs/
American pronunciation/ˌdɛɫəˈtɪɹiəs/
deleterious
[ADJECTIVE]
1

inflicting damage or harm on someone or something

synonyms : hurtful
injurious
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Examples
1Anticipate any deleterious effects.
2So that low estrogen by itself can actually cause some deleterious effects on the bone.
3Every organism carry a load of deleterious mutations.
4This is a deleterious mutation.
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