Definition & Meaning of "keratinocyte"

What is a "keratinocyte"?

A keratinocyte is a specialized cell found in the epidermis of the skin. These cells are responsible for producing keratin, a tough fibrous protein that forms the structural framework of the skin, hair, and nails. Keratinocytes undergo a maturation process as they move toward the surface of the skin, eventually forming the outermost layer of dead skin cells called the stratum corneum. These cells help protect the underlying layers of the skin and contribute to the overall strength and integrity of the skin barrier. Additionally, keratinocytes play a role in immune response and contribute to the regeneration of the skin following injury or damage.