"Huntington's disease" 的定义和意义

What is "Huntington's disease"?

Huntington's disease is a genetic disorder that causes the progressive breakdown of nerve cells in the brain. It is caused by a change in the HTT gene, which leads to the production of an abnormal form of the huntingtin protein. This abnormal protein gradually damages brain cells, leading to symptoms that typically begin in middle age. Symptoms of Huntington's disease include uncontrolled movements, difficulty with coordination and balance, mental decline, and changes in behavior or personality. As the disease progresses, individuals may have trouble with speaking, swallowing, and performing daily activities. There is currently no cure for Huntington's disease, but treatments are available to help manage symptoms and improve quality of life. These may include medications, physical therapy, and supportive care.