The stratum spinosum, also known as the spiny layer, is located between the stratum granulosum and the stratum basale in the epidermis. It is characterized by its unique appearance, with cells appearing spiky or prickly due to the presence of desmosomes. These desmosomes help hold the cells together, contributing to the overall strength and integrity of the skin. The stratum spinosum is involved in the production of keratinocytes, which are essential for the skin's structure and protection.

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