What is a "myeloid-derived suppressor cell"?

A myeloid-derived suppressor cell is a subset of immune cells that arises from the myeloid lineage and possess immunosuppressive properties. They play a role in regulating immune responses and maintaining immune homeostasis, but their excessive accumulation or activation can contribute to immune dysfunction and disease progression. MDSCs are characterized by their ability to suppress T cell activation and promote immune tolerance, making them an important area of research in the field of immunology and cancer immunotherapy.