What is the origin of the idiom "get on one's nerve" and when to use it?

The origin of the phrase "get on one's nerve" can be traced back to the late 19th century. The word "nerve" in this context refers to one's sensitivity or emotional state. The phrase likely emerged from the idea that persistent or irritating stimuli could affect one's nerves, causing discomfort or annoyance. This idiom is commonly employed in interpersonal relationships, such as with family members, friends, or colleagues, to express exasperation or frustration with someone's behavior, habits, or actions that continually test one's patience or sensitivity.