What is the origin of the idiom "in the middle of nowhere" and when to use it?

The idiom "in the middle of nowhere" originated from the literal concept of being situated in a remote or isolated location, far away from populated areas or urban centers. It is used to emphasize the idea of being in a place that lacks human habitation or significant infrastructure. In other words, the phrase conveys a sense of being in a desolate or secluded area, often characterized by vast open spaces, wilderness, or a lack of nearby civilization.