Hodgkin's disease, also known as Hodgkin's lymphoma, is a type of cancer that originates in the lymphatic system, which is part of the body's immune system. It specifically affects a type of white blood cell called lymphocytes. The main sign of Hodgkin's disease is the presence of Reed-Sternberg cells, which are large, abnormal lymphocytes that can be identified under a microscope. Symptoms of Hodgkin's disease can include painless swelling of lymph nodes, fever, night sweats, weight loss, and fatigue. Treatment typically involves chemotherapy, radiation therapy, or a combination of both, and it can be very effective, especially when the disease is detected early. With modern treatments, many people with Hodgkin's disease can get better and stay cancer-free for a long time.

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