Breast cancer gene 2, or BRCA2, is one of the two main genes associated with an increased risk of breast cancer. It is involved in repairing damaged DNA. Changes in this gene mainly increases the risk of breast and ovarian cancers, but they can also increase the risk of other cancers like pancreatic cancer and melanoma. BRCA2 changes also significantly raise the risk of breast cancer in men. Genetic testing for BRCA2 can help evaluate an individual's risk and make appropriate decisions regarding preventive measures or treatments.

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