what's (up) with  somebody or something
what's
wɒts
vots
(up)
ʌp
ap
with
wɪð
vidh
somebody or something

英語での「what's (up) with somebody or something 」の定義と意味

what's (up) with somebody or something
01

used to ask about the reason of something existing or happing 

コロケーション
Hey, what's up with you? You look a bit down today. 
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