Locked-in syndrome is a rare neurological condition where a person is conscious and aware but unable to move or communicate verbally due to complete loss of control over their voluntary muscles, except for eye movements and blinking. This condition typically results from severe damage to the brainstem, often caused by strokes, traumatic brain injuries, or certain neurological disorders. Despite being unable to move or speak, individuals with locked-in syndrome usually retain their mental abilities, including awareness, thinking, and emotions. Communication methods such as eye-tracking devices or blinking in response to questions can allow them to interact with others and express their thoughts and needs. Treatment focuses on providing supportive care, therapy, and assistive technologies to improve quality of life and facilitate communication.

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