Definition & Meaning of "Von Willebrand disease"

What is "Von Willebrand disease"?

Von Willebrand disease is a genetic bleeding disorder that affects the blood's ability to clot properly. It is caused by a lack or problem with von Willebrand factor, a protein that helps blood cells stick together and form clots. Individuals with Von Willebrand disease may experience symptoms such as frequent nosebleeds, easy bruising, prolonged bleeding from minor cuts or injuries, and heavy menstrual bleeding in women. The seriousness of Von Willebrand disease varies depending on the level of von Willebrand factor in the blood and how well it functions. Treatment for Von Willebrand disease may involve medications to increase levels of von Willebrand factor or promote clotting, as well as measures to prevent or control bleeding episodes, such as avoiding certain medications or activities that can increase bleeding risk.